The recent Grenfell Tower fire tragedy has highlighted the importance of fire safety engineering in modern building design. TriVista has recently performed an interesting CFD analysis project predicting both internal building ventilation under specified operating conditions and also smoke contamination in a worst-case fire scenario. The ventilation section of this study had the objective of identifying potential stagnant air locations within the building that could be possibly become hazardous to health owing to the presence of workplace contaminants and emissions. This study was performed for a range of building forced ventilation operating conditions and building design modifications. The smoke stage of the study evaluated the consequences of a worst-case fire and the resulting spread of both heat and smoke. The time variant smoke density and smoke visibility spread was monitored in quantifying the building performance and evaluating countermeasures. For this building CFD study, it is important that the model boundary conditions are accurate and representative of reality to obtain useful results.